Quotes of the Week

January 18, 2021

If we believe that an empirical (experience-based) science — a science grounded in the conceptual ordering of sensible appearances — really does give us genuine knowledge of the world, then a reasonable conclusion is that this world is, by nature, a realm of conceptually ordered appearances possessing the qualities of sense. It asserts its existence and character in the terms of conscious, thought- and sense-derived experience.

(from “A Physicist, a Philosopher, and the Meaning of Life”)

January 11, 2021

[Regarding the nineteenth-century Russian philosopher Vladimir Solovyov’s treatment of evolution:] Consciousness alone is where the evolutionary process is first fully and explicitly realized. Evolution here “comes into its own” and declares itself in human awareness. That which has gone on from the beginning now operates, at least in part, through the conscious choice of the individual and the quest for universal ideals.

In slightly different words: what must be realized through individual human striving today can be seen as an expression — a further development and transformation — of the very processes that were at work in simpler, less individuated life forms. When we observe animals of increasing complexity, we notice a progressive internalization of function and an expansion of interior, sentient life, culminating in self-awareness. That which worked on the organism throughout evolutionary history to develop this capacity for self-awareness, now works through the human being in the exercise of this capacity. Is there any reason to doubt that it is the same power in both cases?

All of which suggests that evolution has had a certain mindful character all along — or a more-than-mindful character, inasmuch as the power to engender minds can hardly be alien or inferior to the capacity of the minds it engenders.

(from “Vladimir Solovyov on Sexual Love and Evolution”)

January 4, 2021

[Concerning the fairly recent researches into “competing endogenous RNAs”:] They participate in a vast “breathing” process, one of whose primary outcomes is the regulation — the balancing and counterbalancing — of the mRNAs themselves in proper relation to ever-changing conditions in the cell and its environment. The challenge for our understanding is considerable when we realize that all these RNAs are (to revise the metaphor only slightly) “swimming” in a common pool, one whose significant eddies and currents can be intricately distinct even as they continually flow one into the other.

The upshot of it all is that protein-coding RNAs are found to share broadly in the fluid life of the organism, and not to be mere cogs in a deterministic mechanism. In particular, they gain additional, noncoding (regulatory) functions, and the sharp distinction between coding and noncoding regions of DNA begins to look even more artificial than it has already become.

(from “RNA: Dancing with a Thousand Partners”)

December 28, 2020

Surely our technological prowess does reflect a practical knowledge of the world. But the pleasure and wonder of it easily blinds us to the fact that we remain infants in fundamental understanding. How often do we remind ourselves that the nature of matter and energy is a mystery to us, or that, when we speak of “the physical”, it is difficult to indicate even roughly what we mean? When we get down to the submicroscopic specifics, we find nothing there, no thing of any recognizable sort. We identify reliable mathematical relations suggesting particular structure, but we do not know: the structure of what?

(from “A Physicist, a Philologist, and the Meaning of Life”)

December 21, 2020

[Owen Barfield, commenting on nineteenth-century philosopher Vladimir Solovyov’s view of sexual attraction and evolution, writes that Solovyov] opens with a biological survey which easily, and to my mind irresistibly, refutes the age-old assumption … that the teleology of sexual attraction is the preservation of the species by multiplication. On the contrary, it is apparent from the whole tendency of biological evolution that nature’s purpose or goal (or whatever continuity it is that the concept of evolution presupposes) has been the development of more complex and, with that, of more highly individualized and thus more perfect organisms. From the fish to the higher mammals quantity of offspring steadily decreases as subtlety of organic structure increases; reproduction is in inverse proportion to specific quality. On the other hand, the factor of sexual attraction in bringing about reproduction is in direct proportion. On the next or sociological level he has little difficulty in showing that the same is true of the factor of romantic passion in sexual attraction. Both history and literature show that it contributes nothing towards the production of either more or better offspring, and may often, as in the case of Romeo and Juliet, actually frustrate any such production at all.

Why then has nature, or the evolutionary process, taken the trouble to bring about this obtrusively conspicuous ingredient in the make-up of homo sapiens?

(from “Vladimir Solovyov on Sexual Love and Evolution”)

December 14, 2020

One finds that in once-isolated and sharply focused areas of molecular biological investigation, the focus is rapidly becoming less sharp. Boundaries are becoming more permeable, so that it is difficult to separate one topic from another. Every “classical” function of a molecule or structure or pathway is turning out to be just one of many different and often (at first) seemingly unrelated functions. Every niche is interwoven with other niches, and the play of “causes” and “effects” is more like the flow of a stream with its endless, interpenetrating eddies than an interaction of discrete machine parts

That’s why terms such as “network”, “systems approach”, “interconnected”, “combinatorial complexity”, and above all “crosstalk” and “context-dependence” now show up with such striking frequency in technical papers. The take-home message is that we’re witnessing a transformation in the way we must think of organisms.

(from “Dancing with a Thousand Partners”)

December 7, 2020

Can the kind of agency we witness so obviously in the development of an individual organism be at all applicable to evolution — that is, to vast populations of co-evolving organisms?

When we speak, not about physical processes as such, but rather about an underlying biological agency, intention, and purposiveness, then the distinction between an individual animal as a collection of molecules, cells, and tissues, on the one hand, and an entire population as a collection of organisms, on the other, becomes an open question. The whole business of telos-directed biological activity, wherever we have observed it, is to bridge radically different physical processes. That is, it brings diverse and complex physical phenomena — for example, in the brain, heart, liver, intestines, and skin of a developing mammal — into integral unity and harmony, making a larger whole of them. When we have seen this purposeful coordination and harmonization in one organic context involving many distinct physical elements, it is only natural to look for it in other organic contexts.

(from “Teleology and Evolution: Why Can’t We Have ‘Evolution on Purpose’?”)

November 30, 2020

When we speak of agency, we speak of capacities we ourselves routinely exercise. But at the same time we must admit that our experience of our own agency is closely bounded on all sides by mystery. We do not fully understand where our thoughts and actions come from, or how our intentions move our bodies. It would be a mistake to clothe the mystery of biological agency in the imagined form of a grandly sovereign, all-knowing human individual.

And if we cannot be entirely clear about the sources of agency in our own lives, we can hardly be dogmatic about the nature of the agency — or diverse agencies — at work in a single bee colony, a particular species of rodent, or the biosphere as a whole. Nothing, however, prevents our being good observers of living beings, which is also to be observers of the clear manifestations of biological agency. In this way we become familiar with the complex and perhaps many-voiced character — the way of being — of particular organisms.

(from “Teleology and Evolution: Why Can’t We Have ‘Evolution on Purpose’?”)

November 16, 2020

This sort of interpenetrability [characteristic of biological agencies] is exactly what we find in language — that is, in different contexts, and even in different words and phrases. We can put words together in infinitely varying ways. Any two words or ideas or philosophies, no matter how different, can be brought into meaningful relation, thereby modifying each other. A word is given its meaning by the character of the larger thought in which it participates, just as a heart receives its meaning from the larger organism in which it participates. Neither the word nor the heart thereby suffers a loss of identity, but rather gains in the richness of its meanings and its relational potentials.

(from “Teleology and Evolution: Why Can’t We Have ‘Evolution on Purpose’?”)

November 9, 2020

An animal’s development from zygote to maturity is a classic picture of telos-realizing activity. Through its agency and purposiveness, an animal holds its disparate parts in an effective unity, making a single whole of them. This purposiveness informs the parts “downward” from the whole and “outward” from the inner intention, and is invisible to strictly physical analysis of the interaction of one part with another.

(from “Teleology and Evolution: Why Can’t We Have ‘Evolution on Purpose’?”)

October 19, 2020

Technology is our hope if we can accept it as our enemy; as our friend it will destroy us. If we look to technology for the solution to our problems, we will only worsen our existing one-sidedness and invite the destruction of everything worth saving. If, on the other hand, we oppose technology with what is not machine-like in ourselves — with an ability to read the world instead of merely manipulating it and losing sight of it — then we will receive from technology the gift of our highest selves.

(from “Owen Barfield and Technological Society”)